Channel 140038-late2

General data

• ICG id: 1154
• ModelDB id: 140038
• Reference: Kovalsky Y, Amir R, Devor M (2009): Simulation in sensory neurons reveals a key role for delayed Na+ current in subthreshold oscillations and ectopic discharge: implications for neuropathic pain.

Metadata classes

• Animal Model: rat
• Brain Area: dorsal root ganglion (DRG)
• Neuron Type: sensory neuron
• Runtime Q: Q1 (fast)
• Subtype: not specified

Metadata generic

• Age: 2-4 weeks
• Authors: M Devor
• Comments: Ttx-sensitive late sodium channel. Models fit to experimental data using hh style kinetics, no apparent modeldb ancestors. Modeling study that is based on previous study (amir et al. 2002), animal model is from there.
• Runtime: 4.544
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp