Channel 112359-hh3

In other classes K

General data

• ICG id: 100
• ModelDB id: 112359
• Reference: Migliore M, Cannia C, Canavier CC (2008): A modeling study suggesting a possible pharmacological target to mitigate the effects of ethanol on reward-related dopaminergic signaling.

Metadata classes

• Animal Model: rat
• Brain Area: basal ganglia, ventral tegmental area (VTA), substantia nigra pars compacta (SNc)
• Neuron Region: soma, dendrites
• Neuron Type: dopaminergic
• Runtime Q: Q4 (slow)
• Subtype: HH

Metadata generic

• Age: not specified
• Authors: A Kuznetsova
• Comments: Squid sodium, potassium delayed rectifier and potassium a channels. Taken from canavier & landry (2006), model no. 84612, with no changes (identical mod file). Modeling study based on a previous model (canavier & landry 2006; komendantov et al. 2004). Animal model comes from these previous studies. In this paper, model is compared to data from mouse midbrain dopamine neurons (okamoto et al. 2006)
• Runtime: 4.844
• Temperature: Model has temperature dependence, with default at 35 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp