Channel 137259-kadist

General data

• ICG id: 989
• ModelDB id: 137259
• Reference: Baker JL, Perez-Rosello T, Migliore M, Barrionuevo G, Ascoli GA (2011): A computer model of unitary responses from associational/commissural and perforant path synapses in hippocampal CA3 pyramidal cells.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: CA3, hippocampus
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: A

Metadata generic

• Age: 4-6 weeks, 23+/-5 days
• Authors: M Migliore.
• Comments: K-a channel from ca1 pyramidal neuron study in migliore et al. (1999), model no. 2796, with no changes (identical model). Used here for ca3 pyramidal neuron model. No modeldb ancestors. Modeling study that uses experimental results from hemond et al. (2008, 2009) and perez-rosello et al. (2011). Animal model here reflects the data in these experimental studies. This channel was adapted from a model of ca1 pyramidal neurons in migliore et al. (1999), model no. 2796.
• Runtime: 7.974
• Temperature: Model has standard temperature dependence. The temperature was 35 deg C for all simulations.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp