Channel 135902-kdrca1

General data

• ICG id: 878
• ModelDB id: 135902
• Reference: Stacey WC, Lazarewicz MT, Litt B (2009): Synaptic noise and physiological coupling generate high-frequency oscillations in a hippocampal computational model.

Metadata classes

• Animal Model: mouse
• Brain Area: CA3, hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: P18-25
• Authors: M Migliore
• Comments: K-dr channel from klee ficker and heinemann, modified to account for dax et al., m migliore 1997. All channel kinetics purportedly taken from tort et al. (2007), model no. 138421, a network model of ca3 hippocampus, with pyramidal, basket, and o-lm cells. Kinetics were originally based on migliore et al. (2004) for pyramidal cells, wang & buzsáki (1996) for basket cells, and saraga et al. (2003) for o-lm cells. No modeldb ancestors. Modeling study, with no mention to experimental results. Model adapted from tort et al. (2007). The animal model info was taken from there.
• Runtime: 7.767
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp