Channel 135839-km

General data

• ICG id: 842
• ModelDB id: 135839
• Reference: Yu Y, Shu Y, McCormick DA (2008): Cortical action potential backpropagation explains spike threshold variability and rapid-onset kinetics.

Metadata classes

• Animal Model: ferret
• Brain Area: somatosensory cortex, layer 5, prefrontal cortex, cortex
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: m

Metadata generic

• Age: 7-10 weeks old
• Authors: Z Mainen
• Comments: Potassium channel, hh style kinetics based on i-m (muscarinic k channel), slow and noninactivating, written by z mainen 1995. Simulations done at 37 deg c. Taken from mainen & sejnowski (1996), model no. 2488, with no changes. The two papers contain electrophysiology results, reflected in the animal model info below, along with modeling study based on previous models.
• Runtime: 7.087
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 23 deg C. SEE NOTE in mod file, should only be used at 37 deg C. Simulations done at 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp