Channel 126640-kaf

General data

• ICG id: 714
• ModelDB id: 126640
• Reference: Spiga S, Lintas A, Migliore M, Diana M (2010): Altered architecture and functional consequences of the mesolimbic dopamine system in cannabis dependence.

Metadata classes

• Animal Model: rat
• Brain Area: basal ganglia, nucleus accumbens (NAcc)
• Neuron Region: soma, dendrites
• Neuron Type: medium spiny projection (MSP) neuron
• Runtime Q: Q2
• Subtype: A

Metadata generic

• Age: not specified
• Authors: J Moyer
• Comments: Fast a-type potassium current for nucleus accumbens (kv4.2), by j moyer 2004, cites tkatch et al (2000). Kinetics for all channels taken from wolf et al. 2005 (112834), with no modification (identical mod file). Animal model is from experiments in paper. Channel kinetics identical to previous study on rat msns, but original source of kinetics may be different (see ancestor models).
• Runtime: 7.557
• Temperature: No apparent temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp