Channel 123453-Kv3

General data

• ICG id: 481
• ModelDB id: 123453
• Reference: Akemann W, Lundby A, Mutoh H, Knopfel T (2009): Effect of voltage sensitive fluorescent proteins on neuronal excitability.

Metadata classes

• Animal Model: mouse
• Brain Area: cerebellum, Purkinje cell layer
• Neuron Type: Purkinje cell
• Runtime Q: Q3
• Subtype: 3

Metadata generic

• Age: P18-27
• Authors: W Akemann
• Comments: Voltage-gated potassium channel from kv3 subunits, high threshold and fast activation/deactivation kinetics. Some params from martina et al. (2007). By w akemann 2007. Modified from previous - bkv3 model was replaced with a hh mechanism. No modeldb ancestors. Experiments on voltage sensors using transfected cells. Model uses previous model of purkinje cell (akemann & knopfel 2006, khaliq et al. 2003). Animal model is from ancestor model. The l5 pyramidal cell model is not included.
• Runtime: 7.75
• Temperature: Model has temperature dependence, with default at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp