Channel 223955-Kv

General data

• ICG id: 4516
• ModelDB id: 223955
• Reference: Ben-Shalom R, Keeshen CM, Berrios KN, An JY, Sanders SJ, Bender KJ (2017): Opposing Effects on NaV1.2 Function Underlie Differences Between SCN2A Variants Observed in Individuals With Autism Spectrum Disorder or Infantile Seizures.

Metadata classes

• Brain Area: cortex
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Subtype: HH

Metadata generic

• Authors: Ben-Shalom R, Keeshen CM,Berrios KN, An JY, Sanders SJ, Bender KJ
• Comments: COMMENT kv.mod Potassium channel, Hodgkin-Huxley style kinetics Kinetic rates based roughly on Sah et al. and Hamill et al. (1991) Author: Zach Mainen, Salk Institute, 1995, zach@salk.edu ENDCOMMENT
• Temperature: q10=2.3, tadj = q10^((celsius - temp)/10)

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp