Channel 223649-IM_cortex

General data

• ICG id: 4504
• ModelDB id: 223649
• Reference: Alturki A, Feng F, Nair A, Guntu V, Nair SS (2016): Distinct current modules shape cellular dynamics in model neurons.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Subtype: m

Metadata generic

• Age: 4-6 weeks old
• Authors: Alturki A, Feng F, Nair A, Guntu V, Nair SS
• Comments: TITLE Cortical M current : : M-current, responsible for the adaptation of firing rate and the : afterhyperpolarization (AHP) of cortical pyramidal cells : : First-order model described by hodgkin-Hyxley like equations. : K+ current, activated by depolarization, noninactivating. : : Model taken from Yamada, W.M., Koch, C. and Adams, P.R. Multiple : channels and calcium dynamics. In: Methods in Neuronal Modeling, : edited by C. Koch and I. Segev, MIT press, 1989, p 97-134. : : See also: McCormick, D.A., Wang, Z. and Huguenard, J. Neurotransmitter : control of neocortical neuronal activity and excitability. : Cerebral Cortex 3: 387-398, 1993. : : Written by Alain Destexhe, Laval University, 1995 :
• Temperature: No temperature dependence

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp