1. Channels
  2. K
  3. 187604-ch_Kdrslow

Channel 187604-ch_Kdrslow

General data

Metadata classes

  • Brain Area: hippocampus
  • Neuron Region: unspecified
  • Neuron Type: pyramidal cell, axo-axonic cell (AAC), basket cell, bistratified cell, fast-spiking (FS) cell, interneuron, oriens alveus (OA)
  • Subtype: delayed rectifier (dr), slow

Metadata generic

  • Authors: Bezaire MJ, Raikov I, Burk K, Vyas D, Soltesz I
  • Comments: TITLE Slow delayed rectifier potassium channel (voltage dependent) COMMENT Slow delayed rectifier potassium channel (voltage dependent) Ions: k Style: quasi-ohmic From: Slow delayed rectifier K+ currents: Storm, 1990: (3) IK activates slowly (time constant, 20–60 ms) in response to depolarizations positive to -40 mV and inactivates (about 5s) at -80 to -40 mV; it probably participates in spike repolarization. (4) IM activates slowly (about 50 ms) positive to -60 mV and does not inactivate; it tends to attenuate excitatory inputs, it reduces the firing rate during maintained depolarization (adaptation) and contributes to the medium after-hyperpolarization (mAHP). Updates: 2014 December (Marianne Bezaire): documented ? ? (Aradi): shifted the voltage dependence by -12 mV - don't know why ENDCOMMENT VERBATIM #include <stdlib.h> /* Include this library so that the following (innocuous) warning does not appear: In function '_thread_cleanup': warning: incompatible implicit declaration of built-in function 'free' */ ENDVERBATIM
  • Temperature: q10 = 3^((celsius - 34)/10)

Current Response Traces

Activation
Inactivation
Deactivation
Action Potential
Ramp

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