Channel 105385-kleak_gp

General data

Metadata classes

  • Animal Model: mouse
  • Brain Area: rostral to midlevel, external globus pallidus (GPe), basal ganglia, globus pallidus (GP)
  • Neuron Type: globus pallidus (GP) neuron
  • Runtime Q: Q1 (fast)
  • Subtype: leak

Metadata generic

  • Age: P17-22
  • Authors: J Held
  • Comments: Leak potassium channel. Ancestry is unclear, no apparent modeldb ancestors. Paper states the following about kinetics: adapted from previous models in migliore et al. (1995), wang et al. (2002), and khaliq et al. (2003), constrained by gp neuron data from baranauskas et al. (1999, 2003), tkatch et al. (2000), chan et al. (2004) and shen et al. (2005). Note that mod files here resemble those of maurice et al. (2004), model no. 98005, but this is not mentioned in paper. Animal model is from experiments in paper. Some channel kinetics were fit to data in paper, or constrained by previous studies of rat globus pallidus neurons (baranauskas et al. 1999, 2003) and others (see paper).
  • Runtime: 6.627
  • Temperature: No temperature dependence. Recordings in paper were done at 22 deg C, simulations were done at 23 deg C.

Current Response Traces

Action Potential