Channel 121060-chan_KIR

General data

• ICG id: 438
• ModelDB id: 121060
• Reference: Steephen JE, Manchanda R (2009): Differences in biophysical properties of nucleus accumbens medium spiny neurons emerging from inactivation of inward rectifying potassium currents.

Metadata classes

• Animal Model: rat
• Brain Area: basal ganglia, nucleus accumbens (NAcc)
• Neuron Region: soma, dendrites
• Neuron Type: medium spiny projection (MSP) neuron
• Runtime Q: Q1 (fast)
• Subtype: inward rectifier (IR, IR2, IRK)

Metadata generic

• Authors: J Moyer
• Comments: Kir channel. Model used previously in wolf et al. (2005), and moyer et al. (2007), paper also cites mermelstein et al. (1998) for channel parameters. Taken from wolf et al. (2005), model no. 112834, with various changes to the mod file. Modeling study based on several previous studies (mermelstein et al. 1999, wolf et al. 2005), which use rat data.
• Runtime: 7.148
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp