Channel 180789-km

General data

• ICG id: 3686
• ModelDB id: 180789
• Reference: Forrest MD (2015): Simulation of alcohol action upon a detailed Purkinje neuron model and a simpler surrogate model that runs >400 times faster.

Metadata classes

• Animal Model: generic
• Brain Area: cerebellum
• Neuron Region: dendrites
• Neuron Type: Purkinje cell
• Subtype: m

Metadata generic

• Authors: MD Forrest
• Comments: Cortical M-current, responsible for the adaptation of firing rate and the afterhyperpolarization of cortical pyramidal cells. First-order model described by Hodgkin-Huxley like equations. K+ current, activated by depolarization, non-inactivating. Model taken from WM Yamada et al, 1989. Written by Alain Destexhe, 1995.
• Temperature: Model has temperature dependence. Model is fit to 36 degC

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp