Channel 117207-IL

General data

• ICG id: 361
• ModelDB id: 117207
• Reference: Acker CD, Antic SD (2009): Quantitative assessment of the distributions of membrane conductances involved in action potential backpropagation along basal dendrites.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: layer 5, prefrontal cortex, cortex
• Neuron Region: axon
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: low threshold

Metadata generic

• Age: P21-P33
• Authors: C Acker
• Comments: Modified from k-a channel of klee ficker and heinemann to be a low-threshold, slowly inactivating current by c acker jun 2006. Designed to mimic data in shu et al. (2007). Adapted from ka channel in migliore et al. (1999), model no. 2796, with various changes. Experimental results mixed with modeling. The animal model info here is from the experiemntal results. Note that the ancestor channels are mostly from hippocampal pyramidal neurons.
• Runtime: 7.92
• Temperature: Model has temperature dependence, simulations done at 30 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp