Channel 155057-kadist

General data

Metadata classes

  • Animal Model: mammal
  • Brain Area: layer 5, prefrontal cortex, cortex
  • Neuron Region: soma, dendrites
  • Neuron Type: pyramidal cell, interneuron
  • Runtime Q: Q3
  • Subtype: A

Metadata generic

  • Age: various
  • Authors: M Migliore, Y Poirazi, C Gold, M Markaki
  • Comments: K-a channel from klee, ficker and heinemann, modified by brannon and y poirazi to account for hoffman et al. (1997) distal region kinetics. Used only in locations > 100 microns from the soma. Modified to work with cvode by c gold, 2003, updated by m markaki, 2003. The paper cites durstewitz et al. (2000), model no. 82849, and durstewitz & gabriel (2007), model no. 82784, as the references for the channel kinetics and mod files for this model. Note that sidiropoulou & poirazi (2012), model no. 144089, also appears to be a reference for many of the files. This file is from sidiropoulou & poirazi (2012), model no. 144089, with no apparent change to parameters or kinetics. Modeling study based on previous models of cortical networks. Model was constrained by various experimental data, see 2013 paper discussion section for a complete list. Most data came from rat, but also some from cat, rabbit and monkey, so the animal model is considered mammalian.
  • Runtime: 7.911
  • Temperature: Model has temperature dependence, with q10 set to 5.0 and original kinetics at 24 deg C.

Current Response Traces

Action Potential