Channel 150284-kir

General data

• ICG id: 3218
• ModelDB id: 150284
• Reference: Mattioni M, Le Novere N (2013): Integration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatum.

Metadata classes

• Animal Model: rat
• Brain Area: basal ganglia, striatum (basal ganglia)
• Neuron Region: soma, dendrites
• Neuron Type: medium spiny projection (MSP) neuron
• Runtime Q: Q2
• Subtype: inward rectifier (IR, IR2, IRK)

Metadata generic

• Age: 48-59 days
• Authors: J Moyer
• Comments: Kir potassium current for nucleus accumbens (irk1=kir2.1) based on the following: mermelstein et al. (1998), uchimura et al. (1989), kubo & murata (2001), and hayashi & fishman (1988). Taken from wolf et al. (2005), model no. 112834, with no changes (identical mod file). Modeling study, uses identical kinetics to ancestor model, so animal model is from there.
• Runtime: 7.574
• Temperature: No apparent temperature dependence. Experiments done at 33-35 deg C, simulations at 35 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp