Channel 149737-kslow

General data

• ICG id: 3197
• ModelDB id: 149737
• Reference: Wang K, Riera J, Enjieu-Kadji H, Kawashima R (2013): The role of extracellular conductivity profiles in compartmental models for neurons: particulars for layer 5 pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: layer 5, cortex
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: slow

Metadata generic

• Age: juvenile (P14-16)
• Authors: A Korngreen
• Comments: Kslow channel, kinetics fit to data from recordings of nucleated patches derived from pyramidal neurons, from keren et al. (2005). By a korngreen, 1998, last updated 2002. Originally from korngreen and sakmann (2000), model no. 3289, with various changes. Mod files appear to have been created independently. Modeling study, with no experimental results. Authors mention that channel parameters were meant to match those of a juvenile rat (pg. 1818), so this is interpreted as the animal model. Otherwise, this can be considered generic.
• Runtime: 8.395
• Temperature: Model has temperature dependence. Original kinetics were at 21 deg C, and q10 is set to 2.3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp