Channel 147867-kdr

General data

• ICG id: 3159
• ModelDB id: 147867
• Reference: Narayanan R, Chattarji S (2010): Computational analysis of the impact of chronic stress on intrinsic and synaptic excitability in the hippocampus.

Metadata classes

• Animal Model: rat, guinea pig
• Brain Area: CA3, hippocampus
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: delayed rectifier (dr)

Metadata generic

• Authors: M Migliore
• Comments: Borg-graham type generic k-dr channel, inactivating. Taken from migliore et al. (1995), model no. 3263, with no changes (identical mod file). Modeling study, uses channel kinetics (migliore et al. 1995, 1999) and experimental data (vyas et al. 2002) from previous studies, mostly using rats and sometimes other animals (guinea pig).
• Runtime: 8.372
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp