Channel 147867-kad

General data

• ICG id: 3156
• ModelDB id: 147867
• Reference: Narayanan R, Chattarji S (2010): Computational analysis of the impact of chronic stress on intrinsic and synaptic excitability in the hippocampus.

Metadata classes

• Animal Model: rat, guinea pig
• Brain Area: CA3, hippocampus
• Neuron Region: dendrites, distal dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: A

Metadata generic

• Authors: M Migliore
• Comments: K-a distal channel from migliore et al. (1999), model no. 2796, with the following changes: parameter nmin chained (line 29), removal of belt function, although it was not used in ancestor model. Modeling study, uses channel kinetics (migliore et al. 1995, 1999) and experimental data (vyas et al. 2002) from previous studies, mostly using rats and sometimes other animals (guinea pig).
• Runtime: 8.117
• Temperature: Model has temperature dependence, default at 24 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp