Channel 151458-kir

General data

• ICG id: 3045
• ModelDB id: 151458
• Reference: Nakano T, Yoshimoto J, Doya K (2013): A model-based prediction of the calcium responses in the striatal synaptic spines depending on the timing of cortical and dopaminergic inputs and post-synaptic spikes.

Metadata classes

• Animal Model: mouse
• Brain Area: basal ganglia, striatum (basal ganglia)
• Neuron Type: medium spiny projection (MSP) neuron
• Runtime Q: Q2
• Subtype: inward rectifier (IR, IR2, IRK)

Metadata generic

• Age: P21-25
• Authors: J Moyer
• Comments: Kir potassium current for nucleus accumbens (irk1=kir2.1), based on several previous studies including mermelstein et al. (1998), uchimura et al. (1989), kubo & murata (2001), and hayashi & fishman (1998). Taken from wolf et al. (2005), model no. 112834, with the addition of variable mu (lines 61, 67). Modeling study, the animal model here is from the morphology explained in this paper. Channel kinetics based on previous model of msp in nucleus accumbens of rats.
• Runtime: 7.454
• Temperature: No apparent temperature dependence. Set to 35 deg C with qfact of 0.5.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp