Channel 147757-kaprox

General data

• ICG id: 3005
• ModelDB id: 147757
• Reference: Romani A, Marchetti C, Bianchi D, Leinekugel X, Poirazi P, Migliore M, Marie H (2013): Computational modeling of the effects of amyloid-beta on release probability at hippocampal synapses.

Metadata classes

• Animal Model: rat, Long Evans
• Brain Area: CA3, hippocampus
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: A

Metadata generic

• Age: unknown
• Authors: Brannon, Y Porazi, C Gold, M Markaki.
• Comments: Ka channel from klee, ficker and heinemann. Modified by brannon and y poirazi to account for hoffman et al. 1997 distal region kinetics. Updated by c gold, m markaki. From bianchi et al. (2012), model no. 143719, with no changes (identical mod file). Used in soma and proximal dendrites. Animal model from experiments in this paper, model originally for ca1 pyramidal neuron.
• Runtime: 8.35
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp