Channel 150240-IM

General data

• ICG id: 2966
• ModelDB id: 150240
• Reference: Behuret S, Deleuze C, Gomez L, Fregnac Y, Bal T (2013): Cortically-controlled population stochastic facilitation as a plausible substrate for guiding sensory transfer across the thalamic gateway.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: cortex, retina, thalamocortical circuit, layer 4
• Neuron Region: unspecified
• Neuron Type: pyramidal cell, thalamocortical relay cell (TC, TCR)
• Runtime Q: Q2
• Subtype: m

Metadata generic

• Age: 4-6 weeks, 14-25 days
• Authors: A Destexhe
• Comments: Cortical m current. Taken from yamada et al. (1989), see also mccormick et al. (1993), which the paper cites. Written by a destexhe, 1995. Ancestor channel is from destexhe et al. (1998, 2001), model no 3817, with the following change: solver method changed from cnexp to euler (line 59). Paper features in vitro experiments on rat thalamus, which are used along with the model. Parameter values for active kinetics may have been modified to fit voltage clamp data in this paper.
• Runtime: 7.337
• Temperature: q10 assumed to be 2.3 in this model, temperature of 36 deg C is default, modified by this q10.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp