Channel 145672-migliore_kaprox

General data

• ICG id: 2814
• ModelDB id: 145672
• Reference: Fineberg JD, Ritter DM, Covarrubias M (2012): Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites, proximal dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: A

Metadata generic

• Age: 5-8 weeks
• Authors: M Migliore
• Comments: K-a channel for proximal dendrites from migliore et al. (1999), model no. 2796, with no changes (identical mod files). Animal model is from ancestor (migliore et al. 1999). Experiments in this paper were done on granule neurons (cgn) and dorsal root ganglion neurons (drg), but these were not modeled explicitly.
• Runtime: 7.968
• Temperature: Model has temperature dependence, with default kinetics at 24 deg C, and q10 set to 5.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp