Channel 144976-kaprox

General data

• ICG id: 2807
• ModelDB id: 144976
• Reference: Culmone V, Migliore M (2012): Progressive effect of beta amyloid peptides accumulation on CA1 pyramidal neurons: a model study suggesting possible treatments.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites, proximal dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: A

Metadata generic

• Age: 50 days old
• Authors: M Migliore
• Comments: K-a channel, identical to the one in migliore et al. (2008), model no. 87535, originally from migliore et al. (1999). Modeling study, identical to ancestor model, the animal model info is from the morphology used here.
• Runtime: 8.047
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp