Channel 141063-sdsr

In other classes Na

General data

• ICG id: 2750
• ModelDB id: 141063
• Reference: Orio P, Parra A, Madrid R, Gonzalez O, Belmonte C, Viana F (2012): Role of Ih in the firing pattern of mammalian cold thermoreceptor endings.

Metadata classes

• Animal Model: mouse
• Brain Area: peripheral NS
• Neuron Region: unspecified
• Neuron Type: cold thermoreceptor nerve ending
• Runtime Q: Q4 (slow)
• Subtype: slow

Metadata generic

• Age: not specified
• Authors: P Orio
• Comments: Isd and isr currents of the huber-braun model, from braun et al., slow and subthreshold-activated na and k currents responsible for oscillation non-inactivating inap. Sr (slow potassium) conductance was modified adding a saturating function now asr resembles calcium concentration and ik is a hill function of asr, therefore asr can be greater than 1 without making the open prob of kca greater than one. No modeldb ancestors. Animal model is from experiments in paper.
• Runtime: 5.286
• Temperature: Model has temperature dependence, with original kinetics at 25 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp