Channel 116084-kaprox

General data

• ICG id: 2715
• ModelDB id: 116084
• Reference: Jarsky T, Roxin A, Kath WL, Spruston N (2005): Conditional dendritic spike propagation following distal synaptic activation of hippocampal CA1 pyramidal neurons.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites, proximal dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: A

Metadata generic

• Age: 55-57 days old
• Authors: M Migliore
• Comments: K-a channel originally from migliore et al. (1999). Paper references migliore et al. (1999), model no. 2796, and golding et al. (2001), model no. 64167, as references for active kinetics. Mod file is identical to the one in golding et al., so that is listed as the ancestor channel. Model here taken from two previous studies, the animal model info comes from the experimental results in this paper.
• Runtime: 8.401
• Temperature: Model has standard temperature dependence. Experiments done at 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp