Channel 115356-km

General data

• ICG id: 266
• ModelDB id: 115356
• Reference: Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008): Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: soma, axon
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: m

Metadata generic

• Age: 17-21 days
• Authors: M Horstmann.
• Comments: K-strom, i_m, warman (1994), ek martina, t-dependence from halliwell, adams 1982. No model db ancestors. Experimental study along with modeling, with morphology from varona et al. (2000) and kinetics from golomb et al. (2006). The animal model info here is from the experiments in this paper.
• Runtime: 7.213
• Temperature: Model has temperature dependence, with default temperature of 23 deg C, and q10 from Halliwell and Adams (1982).

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp