Channel 98005-kir2_ch

General data

• ICG id: 2648
• ModelDB id: 98005
• Reference: Maurice N, Mercer J, Chan CS, Hernandez-Lopez S, Held J, Tkatch T, Surmeier DJ (2004): D2 dopamine receptor-mediated modulation of voltage-dependent Na+ channels reduces autonomous activity in striatal cholinergic interneurons.

Metadata classes

• Animal Model: Sprague-Dawley, mouse, rat, C57BL/6
• Brain Area: basal ganglia, striatum (basal ganglia)
• Neuron Region: soma, dendrites
• Neuron Type: interneuron, cholinergic
• Runtime Q: Q1 (fast)
• Subtype: inward rectifier (IR, IR2, IRK)

Metadata generic

• Age: 3-5 weeks
• Authors: J Held
• Comments: Kir2 inwardly rectifying channel. This is not mentioned in the paper, ancestry is unclear. Animal model is from experiments in paper.
• Runtime: 7.266
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp