Channel 97860-kv2_hh

General data

• ICG id: 2566
• ModelDB id: 97860
• Reference: Chan CS, Guzman JN, Ilijic E, Mercer JN, Rick C, Tkatch T, Meredith GE, Surmeier DJ (2007): 'Rejuvenation' protects neurons in mouse models of Parkinson's disease.

Metadata classes

• Animal Model: mouse
• Brain Area: basal ganglia, substantia nigra pars compacta (SNc)
• Neuron Region: single compartment
• Neuron Type: dopaminergic
• Runtime Q: Q3
• Subtype: 2.1

Metadata generic

• Age: adult (<P28), juvenile (<P21)
• Authors: J Held
• Comments: Hh-style kv2.1 channel model with inactivation, no apparent model db ancestors. Animal model comes from experiments in paper. Channel kinetics are mostly from unspecified sources.
• Runtime: 7.98
• Temperature: Model has temperature dependence, with original kinetics at 23 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp