Channel 102288-Ikdrsaxon

General data

• ICG id: 25
• ModelDB id: 102288
• Reference: Lawrence JJ, Saraga F, Churchill JF, Statland JM, Travis KE, Skinner FK, McBain CJ (2006): Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: oriens lacunosum-moleculare (O-LM), interneuron
• Runtime Q: Q3
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: 3-6 months old
• Authors: M Migliore
• Comments: Slow k-dr current for hippocampal interneurons from lien et al (2002), model no. 20015, with no apparent modification to kinetics implemented by m migliore jan 2003. Note, there does not appear to be a difference between this channel and ikdrf.mod. Experimental results for im potassium current along with modeling. The animal model info here is from experimental results in the paper.
• Runtime: 7.804
• Temperature: Model has temperature dependence, with original kinetics at 23 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp