Channel 8210-kd3h5

General data

Metadata classes

  • Animal Model: mammal
  • Brain Area: layer 5, cortex
  • Neuron Region: soma, dendrites, basal dendrites
  • Neuron Type: pyramidal cell
  • Runtime Q: Q1 (fast)
  • Subtype: HH

Metadata generic

  • Age: generic
  • Authors: ZF Mainen
  • Comments: Noninactivating potassium current. Equations based on hodgkin-huxley (1952) formulation, with activation kinetics analogous to 8210_na3h5. Likely based on mccormick and huguenard (1992), as with na+, though this is not explicity stated for the k current. Kinetic rates based roughly on sah et al. And hamill et al. (1991). Modeling study, with dendritic morphology based on rat l5 pyramidal neuron, from d. Smetters and s. Nelson (unpublished). Geometry of initial segment based on cat layer 5 pyramidal cell (fariã±as and defelipe 1991). Two experimental references listed for the channels themselves, from rat cerebral cortex and guinea pig hippocampal ca1 neurons. The model is considered generic for this reason.
  • Runtime: 7.042
  • Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 16 deg C.

Current Response Traces

Action Potential