Channel 8115-IM

General data

• ICG id: 2372
• ModelDB id: 8115
• Reference: Destexhe A, Rudolph M, Fellous JM, Sejnowski TJ (2001): Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons.

Metadata classes

• Animal Model: cat
• Brain Area: prefrontal cortex, cortex, parietal cortex
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: m

Metadata generic

• Age: 2-4 weeks
• Authors: A Destexhe
• Comments: Cortical muscarinic potassium current: noninactivating k+ current responsible for adaptation of firing rate and slow afterhyperpolarization (ahp), hh-like. Model from mainen and sejnowski 1996, written by a destexhe 1996. Paper cites hodgkin-huxley (1952) as well as destexhe and paré (1999). Does not appear to derive from km.mod from mainen & sejnowski (1996). No modeldb ancestors. Animal model comes from the in vitro experiments in paper. Note that model morphology comes from previous study of cat parietal cortex neurons (layers 2/3, 5, 6) from douglas et al. 1991, and contreras et al. 1997.
• Runtime: 7.317
• Temperature: Model has temperature dependence, default at 36 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp