Channel 114394-Km
General data
- ICG id: 230
- ModelDB id: 114394
- Reference: Kole MH, Ilschner SU, Kampa BM, Williams SR, Ruben PC, Stuart GJ (2008): Action potential generation requires a high sodium channel density in the axon initial segment.
Metadata classes
- Animal Model: Wistar, rat
- Brain Area: somatosensory cortex, layer 5, cortex
- Neuron Region: soma, dendrites, axon, axon hillock, axon initial segment (AIS)
- Neuron Type: pyramidal cell
- Runtime Q: Q1 (fast)
- Subtype: m
Metadata generic
- Age: 2-4 weeks old
- Authors: Z Mainen
- Comments: Potassium channel, h-h style kinetics based on i-m (muscarinic k channel), slow and noninactivating, written by z mainen. Paper cites mainen et al. (1995), model no. 8210, but this appears to come from mainen & sejnowski (1996), model no. 2488, with various changes to mod file, but similar kinetics. This paper contains experimental results from rats, as well as modeling based on a previous model. The animal model info here is from the experimental results, the morphology of the model is not specified, could also come from the ancestor model.
- Runtime: 6.802
- Temperature: Model has temperature dependence, with original kinetics at 23 deg C, and q10 set to 2.3. Simulations done here at 37 deg C.