Channel 114394-Km
General data
- ICG id: 230
- ModelDB id: 114394
- Reference: Kole MH, Ilschner SU, Kampa BM, Williams SR, Ruben PC, Stuart GJ (2008): Action potential generation requires a high sodium channel density in the axon initial segment.
Metadata classes
- Animal Model: Wistar, rat
- Brain Area: somatosensory cortex, layer 5, cortex
- Neuron Region: soma, dendrites, axon, axon hillock, axon initial segment (AIS)
- Neuron Type: pyramidal cell
- Runtime Q: Q1 (fast)
- Subtype: m
Metadata generic
- Age: 2-4 weeks old
- Authors: Z Mainen
- Comments: Potassium channel, h-h style kinetics based on i-m (muscarinic k channel), slow and noninactivating, written by z mainen. Paper cites mainen et al. (1995), model no. 8210, but this appears to come from mainen & sejnowski (1996), model no. 2488, with various changes to mod file, but similar kinetics. This paper contains experimental results from rats, as well as modeling based on a previous model. The animal model info here is from the experimental results, the morphology of the model is not specified, could also come from the ancestor model.
- Runtime: 6.802
- Temperature: Model has temperature dependence, with original kinetics at 23 deg C, and q10 set to 2.3. Simulations done here at 37 deg C.
Current Response Traces
Activation

Inactivation

Deactivation

Action Potential

Ramp
