Channel 64212-kavn

General data

• ICG id: 2190
• ModelDB id: 64212
• Reference: Shimazaki R, Boccaccio A, Mazzatenta A, Pinato G, Migliore M, Menini A (2006): Electrophysiological properties and modeling of murine vomeronasal sensory neurons in acute slice preparations.

Metadata classes

• Animal Model: mouse, 129/Sv
• Brain Area: vomerunasal organ
• Neuron Region: unspecified
• Neuron Type: sensory neuron
• Runtime Q: Q4 (slow)
• Subtype: A

Metadata generic

• Age: 30-90 days old
• Authors: M Migliore
• Comments: K-a current for mitral cells from wang et al. (1996), model no. 3648, written by m. Migliore jan 2002, adapted for vn neurons 2005. Experimental results from mice, coupled with a model originally for mitral cells which was adapted for vno neurons. The animal model info here is from the experimental methods in this paper. Note that the morphology used in the neuron was made simply with a soma and cylindrical dendrite.
• Runtime: 8.126
• Temperature: Model has temperature dependence, with q10 set to 3 and original kinetics at 22 deg C.Experiments done at 20-23 deg C, simulations at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp