Channel 64195-km

General data

• ICG id: 2185
• ModelDB id: 64195
• Reference: Kole MH, Hallermann S, Stuart GJ (2006): Single Ih channels in pyramidal neuron dendrites: properties, distribution, and impact on action potential output.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: somatosensory cortex, layer 5, cortex
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: m

Metadata generic

• Age: 28-70 days
• Authors: Z Mainen
• Comments: Potassium channel, h-h kinetics based on i-m (muscarinic k channel), slow and noninactivating. Written by z mainen 1995. Taken from schaefer et al. (2003), model no. 83344, with different integration method and implementation of temperature dependence. Experimental data to get info for ih currents, model very similar to ancestor. The animal model info here is from the experimental procedures.
• Runtime: 7.378
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 23 deg C. Simulation temperature was 35 deg C, experimental procedures at 33-35 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp