Channel 62285-KDRI

General data

• ICG id: 2173
• ModelDB id: 62285
• Reference: Melnick IV, Santos SF, Szokol K, Szucs P, Safronov BV (2004): Ionic basis of tonic firing in spinal substantia gelatinosa neurons of rat.

Metadata classes

• Animal Model: rat
• Brain Area: lumbar enlargement, spinal cord
• Neuron Type: motoneuron
• Runtime Q: Q1 (fast)
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: 2-5 week old
• Authors: B Safronov
• Comments: Looks like the k-a channel, modified from b_a.mod in safronov et al. (2000), model no. 62266, but with gkbar set to zero and slightly different parameters for kinetic equations. Note: in the paper it says that the ka current was negligible and so not included in the model at all. Experimental results and model, largely from ancestor model. The animal model info here is from experimental methods.
• Runtime: 7.199
• Temperature: Model has temperature dependence, with original kinetics at 6.3 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp