Channel 46839-grc_kir

General data

• ICG id: 2019
• ModelDB id: 46839
• Reference: D'Angelo E, Nieus T, Maffei A, Armano S, Rossi P, Taglietti V, Fontana A, Naldi G (2001): Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism.

Metadata classes

• Animal Model: rat
• Brain Area: granule cell layer, cerebellum
• Neuron Region: single compartment
• Neuron Type: granule cell
• Runtime Q: Q4 (slow)
• Subtype: inward rectifier (IR, IR2, IRK)

Metadata generic

• Age: 18-22 days old
• Authors: E D'Angelo.
• Comments: Fast inward rectifier current for cerebellum granule cell model. Reconstructed from data reported in rossi et al. (1998). This paper contains experimental results from recordings in rat cerebellar slices (18-22 days old). This channel's kinetics are from rossi et al. (1998), a study on mouse cerebellar granule cells.
• Runtime: 8.929
• Temperature: Model has temperature dependence. Experiments done at room temperature and simulations done at 30 deg C, with q10=3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp