Channel 46839-grc_ka

General data

• ICG id: 2018
• ModelDB id: 46839
• Reference: D'Angelo E, Nieus T, Maffei A, Armano S, Rossi P, Taglietti V, Fontana A, Naldi G (2001): Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism.

Metadata classes

• Animal Model: rat
• Brain Area: granule cell layer, cerebellum
• Neuron Region: single compartment
• Neuron Type: granule cell
• Runtime Q: Q4 (slow)
• Subtype: A

Metadata generic

• Age: 18-22 days old
• Authors: E D'Angelo.
• Comments: Fast-activating, fast-inactivating voltage-dependent k+ current for cerebellum granule cell model. Model reproduced from data in bardoni and belluzzi (1993). Simulation temperature of 30 deg c. This paper contains experimental results from recordings in rat cerebellar slices (18-22 days old), but the ka channel was created from previous data, also using rat cerebellar slices (age 10-20 days old). (bardoni & belluzzi, 1993).
• Runtime: 10.653
• Temperature: Model has temperature dependence. Experiments done at room temperature and simulations done at 30 deg C, with q10=3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp