Channel 113732-km

General data

• ICG id: 188
• ModelDB id: 113732
• Reference: Jones SR, Pritchett DL, Stufflebeam SM, Hamalainen M, Moore CI (2007): Neural correlates of tactile detection: a combined magnetoencephalography and biophysically based computational modeling study.

Metadata classes

• Animal Model: human
• Brain Area: somatosensory cortex, layer 5, layer 2/3, cortex
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell, inhibitory, interneuron
• Runtime Q: Q1 (fast)
• Subtype: m

Metadata generic

• Age: adult (18-45 years old)
• Authors: Z Mainen
• Comments: Potassium channel, h-h style kinetics based on i-m (muscarinic k channel), slow and noninactivating. Written by z mainen, 1995. Taken from mainen & sejnowski (1996), model no. 2488, with potential changes to kinetics. Experimental data, meg imaging of humans, with modeling of layer 2/3 and layer 5 pns, morphology adapted from bush and sejnowski (1993) from cat visual cortex, originally from koch et al. (1990). The animal model info here is from the experimental procedures here.
• Runtime: 7.107
• Temperature: Model has temperature dependence, with q10 at 2.3 and default temperature of 23 deg C. HOWEVER see comment in mod file of model 2488, model should only be run at 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp