Channel 3454-ht

General data

• ICG id: 1816
• ModelDB id: 3454
• Reference: Wang LY, Gan L, Forsythe ID, Kaczmarek LK (1998): Contribution of the Kv3.1 potassium channel to high-frequency firing in mouse auditory neurones.

Metadata classes

• Animal Model: mouse
• Brain Area: medial nucleus of trapezoid body (MNTB) (brainstem)
• Neuron Type: MNTB neuron
• Runtime Q: Q4 (slow)
• Subtype: 3.1

Metadata generic

• Age: P8-14
• Authors: D Kornfeld
• Comments: High threshold potassium channel (kv3.1). Parameters slightly modified from kanemasa et al. 1995 and perney & kaczmarek 1997 for kv3.1 currents in nih-3t3 cells, obtained from direct fits to recorded traces. Rapid activation and deactivation kinetics. No modeldb ancestors. Animal model is from experiments in paper. Channel kinetics adapted from previous models, fit do traces in this paper.
• Runtime: 8.18
• Temperature: No temperature dependence. Experiments were done at room temperature (20-22 deg C), used to fit kinetics.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp