Channel 3342-kd

General data

• ICG id: 1785
• ModelDB id: 3342
• Reference: Shen GY, Chen WR, Midtgaard J, Shepherd GM, Hines ML (1999): Computational analysis of action potential initiation in mitral cell soma and dendrites based on dual patch recordings.

Metadata classes

• Animal Model: rat
• Brain Area: mitral cell layer, olfactory bulb (OB)
• Neuron Region: soma, dendrites, axon, axon hillock, axon initial segment (AIS), primary dendrites, dendritic tuft (apical tuft), axon nodes (nodes of ranvier), secondary dendrites
• Neuron Type: mitral cell
• Runtime Q: Q1 (fast)
• Subtype: not specified

Metadata generic

• Age: 18-28 days
• Authors: Z Mainen, M Hines
• Comments: Potassium channel from mainen et al (1995), model no. 8210, with the following changes: parameters gbar, tha, qa, ra, rb have been modified (lines 34, 37, 38, 40, 41), activation kinetics are to the fourth power (line 74), and modified states and trates procedures. Experimental results as well as modeling (expts described in chen et al. 1997). Morphology for model was created using known characteristics about mitral cells. The animal model info here is from the experimental methods.
• Runtime: 7.013
• Temperature: Model has temperature dependence, with original kinetics at 16 deg C, and q10 set to 2.3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp