Channel 22203-km

General data

• ICG id: 1692
• ModelDB id: 22203
• Reference: Schaefer AT, Helmstaedter M, Schmitt AC, Bar-Yehuda D, Almog M, Ben-Porat H, Sakmann B, Korngreen A (2007): Dendritic voltage-gated K+ conductance gradient in pyramidal neurones of neocortical layer 5B from rats.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: somatosensory cortex, layer 5, cortex
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: m

Metadata generic

• Age: 40-45 days old
• Authors: Z Mainen
• Comments: Potassium channel, h-h style kinetics, based on i-m (muscarinic k channel), slow noninactivating. Implemented by z mainen 1995. Paper cites mainen et al. (1995), model no. 8210, but this does not have a km channel. Actual ancestor is mainen & sejnowski (1996), model. No 2488, with possible modification. This study features experimental results as well as modeling, the animal model below reflects the experimental results, although the animal model and neuron are the same as the ancestor.
• Runtime: 6.714
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp