Channel 20212-hha_old

In other classes Na

General data

• ICG id: 1645
• ModelDB id: 20212
• Reference: Polsky A, Mel BW, Schiller J (2004): Computational subunits in thin dendrites of pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: dendrites, apical trunk, basal dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: HH

Metadata generic

• Authors: Y Poirazi
• Comments: Hh channel that includes both a sodium and a delayed rectifier channel and accounts for sodium conductance attenuation. Modified several times, see mod file. Used in all but somatic and axon sections. Adapted from bernander et al. (1991), dendritic location-dependent slow attenuation of sodium current (jung et al. 1997; migliore et al 1999). No apparent modeldb ancestors. This is a modeling study, and the animal model is considered to be rat. The authors compare the model to experimental results mostly in rats (e.g. Magee 1998, spruston et al. 1995) and the morphology used is also from rat (2 months old, cannon et al. 1998, n123). Channel kinetics come from various sources.
• Runtime: 4.484
• Temperature: Model has temperature dependence. Simulations were done at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp