Channel 20015-kdrs

General data

• ICG id: 1606
• ModelDB id: 20015
• Reference: Lien CC, Martina M, Schultz JH, Ehmke H, Jonas P (2002): Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: hippocampus, CA1, stratum oriens-alveus
• Neuron Region: unspecified
• Neuron Type: interneuron, oriens alveus (OA)
• Runtime Q: Q4 (slow)
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: 13-22 days old
• Authors: M Migliore
• Comments: Slow k-dr current for hippocampal interneurons from lien et al. (2002). Implemented by m. Migliore jan 2003. Kinetics from this paper, no model db ancestors. This is an experimental paper (animal model info here), which was made into a model later.
• Runtime: 8.025
• Temperature: Model has standard temperature dependence qith q10=3. Experiments for kinetics done at 20-24 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp