Channel 20015-ka

General data

• ICG id: 1604
• ModelDB id: 20015
• Reference: Lien CC, Martina M, Schultz JH, Ehmke H, Jonas P (2002): Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: hippocampus, CA1, stratum oriens-alveus
• Neuron Region: unspecified
• Neuron Type: interneuron, oriens alveus (OA)
• Runtime Q: Q3
• Subtype: A

Metadata generic

• Age: 13-22 days old
• Authors: M Migliore
• Comments: K-a current (rapidly inactivating) for hippocampal interneurons from lien et al. (2002). Implemented by m. Migliore jan 2003. Expt suggests this current is mediated by kv3.2 and kv4.3 channels. Kinetics from this paper, no model db ancestors. This is an experimental paper (animal model info here), which was made into a model later.
• Runtime: 7.804
• Temperature: Model has standard temperature dependence qith q10=3. Experiments for kinetics done at 20-24 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp