Channel 20007-KaDM99SL
General data
- ICG id: 1590
- ModelDB id: 20007
- Reference: Lazarewicz MT, Migliore M, Ascoli GA (2002): A new bursting model of CA3 pyramidal cell physiology suggests multiple locations for spike initiation.
Metadata classes
- Animal Model: rat
- Brain Area: CA3, hippocampus
- Neuron Region: dendrites, distal dendrites
- Neuron Type: pyramidal cell
- Runtime Q: Q3
- Subtype: A
Metadata generic
- Age: 33-57 days old
- Authors: M Migliore
- Comments: K-a channel from migliore et al. (1999), model no. 2796 (from klee, ficker and heinemann (1995) as well as hoffman et al. (1997), modified to account for dax a current). By m. Migliore jun 1997. Kinetics from milgiore et al. (1999), distribution from hoffman et al. (1997). Note that the hill coefficient (q10) used in kinetics corresponds to a temperature of 25 deg c. The following modifications exist from ancestor model: nmin changed to 0.1 (line 23), ek set to 90.0 (line 56). Strictly a modeling study, in which the ancestor ca1 model is adapted to a ca3 morphology. The animal model info below is from the morphology used here, from ishizuka et al. (1990).
- Runtime: 7.971
- Temperature: Model has temperature dependence. Hill coefficient (Q10) used in kinetics corresponds to a temperature of 25 deg C for simulation.
Current Response Traces
Activation
Inactivation
Deactivation
Action Potential
Ramp
