Channel 144526-Kv

General data

• ICG id: 1473
• ModelDB id: 144526
• Reference: Hallermann S, de Kock CP, Stuart GJ, Kole MH (2012): State and location dependence of action potential metabolic cost in cortical pyramidal neurons.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 5, cortex
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: HH

Metadata generic

• Age: 3-5 weeks old
• Authors: Z Mainen, S Hallermann, M Kole
• Comments: Potassium channel, hh style kinetics, based roughly on sah et al. And hamill et al. (1991), written by z mainen 1995. Described as similar to kv2. Adapted from mainen & sejnowski (1996), model no. 2488. Electrophysiological recordings with modeling from previously created models. The animal model info is from the experimental data. The neuronal morphology for the model came from experimental reports from in vivo and in vitro l5 pyramidal neurons.
• Runtime: 7.151
• Temperature: Simulations done at 33 deg C and 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp