Channel 143719-km

General data

• ICG id: 1261
• ModelDB id: 143719
• Reference: Bianchi D, Marasco A, Limongiello A, Marchetti C, Marie H, Tirozzi B, Migliore M (2012): On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, axon
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: m

Metadata generic

• Age: P19-24
• Authors: M Migliore
• Comments: Ca1 km channel from mala shah, implemented by m migliore jun 2006. From shah et al. (2008), model no. 112546, with modification to parameters vhalfl, kt, a0t, zetat and gmt (lines 15-26). Experimental and modeling results in this paper. The animal model info here is from the experimental results, morphology was reduced to a single compartment.
• Runtime: 7.711
• Temperature: Model has temperature dependence

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp