Channel 143719-kdr

General data

• ICG id: 1260
• ModelDB id: 143719
• Reference: Bianchi D, Marasco A, Limongiello A, Marchetti C, Marie H, Tirozzi B, Migliore M (2012): On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: P19-24
• Authors: M Migliore
• Comments: K-dr channel from klee ficker and heinemann, modified to account for dax et al., implemented by m migliore 1997. From shah et al. (2008), model no. 112546, with no modification to kinetics. Experimental and modeling results in this paper. The animal model info here is from the experimental results, morphology was reduced to a single compartment.
• Runtime: 7.718
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp