Channel 143442-kv

General data

• ICG id: 1235
• ModelDB id: 143442
• Reference: Foust AJ, Yu Y, Popovic M, Zecevic D, McCormick DA (2011): Somatic membrane potential and Kv1 channels control spike repolarization in cortical axon collaterals and presynaptic boutons.

Metadata classes

• Animal Model: mouse
• Brain Area: somatosensory cortex, layer 5, cortex
• Neuron Region: axon, axon initial segment (AIS), axon nodes (nodes of ranvier)
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: HH

Metadata generic

• Age: 2-5 weeks old
• Authors: Z Mainen
• Comments: Potassium channel, hh style kinetics, from mainen et al. (1995), as well as yu et al. (2008), model no. 135839. Several changes exist from ancestor channel. Experimental results and modeling. The animal model info here is from the experimental methods.
• Runtime: 7.014
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 23 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp